Introductions and Early Spread of SARS-CoV-2 in France, 24 January to 23 March 2020

Epidemiology TransversalVirology
Gambaro F et al

Main result

The virus has been introduced into northern France several times by travellers arriving from abroad. The sequences are mainly divided into 3 clades. Isolation measures for symptomatic individuals led to the extinction of 2 clades. However, they did not prevent the development of one clade, probably due to the presence of asymptomatic infected cases.


SARS-Cov-2 virus has been introduced several times into northern France by travellers arriving from abroad. Measures to isolate symptomatic individuals allowed to control several virus introductions, but they have not prevented the development of the epidemic.

Strength of evidence Undetermined

Data from this study appear to be available. It would be interesting to reanalyze them with phylodynamic models to estimate demographic or genetic parameters of the virus. But perhaps this has already been done by teams working on the phylodynamics of the virus? Since the data contain the locations where the sequences were collected, a spatial structure could be introduced into the model.


To study how the SARS-Cov-2 epidemic started in the north of France.


Data: 97 SARS-Cov-2 sequences collected from symptomatic individuals in northern France between 24/01/2020 and 24/03/2020. Method: Phylogenetic analyses.

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