13.05.2020

Abdominal Imaging Findings in COVID-19: Preliminary Observations

Diagnostic Hepato-gastroenterologyRadiology
Bhayana R et al
Radiology

Main result

Inclusion of 412 patients (mean age 57 years, 58.5% male, 136 (33%) admitted to intensive care). 134 patients (33%) received abdominal imaging (total of 224 images: 137 X-rays, 44 ultrasounds, 42 computed tomography (CT) scans, 1 MRI).

Abdominal imaging was associated with age (OR 1.03 per year plus, p = 0.001) and admission to intensive care (OR 17.3, p < 0.001). Bowel wall abnormalities were observed on 13 CT scans (31%) and were associated with admission to the intensive care unit (OR 15.5, p = 0.01). Intestinal findings included pneumatosis or portal vein gas, observed on 20% of the CT scans in intensive care patients (4 of 20). Surgical exploration (n = 4) revealed unusual yellow discoloration of the bowel (n = 3) and intestinal infarction (n = 2). Pathology revealed ischemic enteritis with uneven necrosis and fibrin thrombus in the arterioles (n = 2). For right upper quadrant ultrasound, 87% (32 out of 37) were performed to explore abnormal liver biology findings, and 54% (20 out of 37) showed a dilated gallbladder filled with sludge suggesting cholestasis. Patients with cholecystostomy (n = 4) had negative bacterial cultures.

Takeaways

Intestinal abnormalities and cholestasis were common images in hospitalized patients. Patients who underwent laparotomy often had ischemia, probably related to small vessel thrombosis.

Strength of evidence Weak

Descriptive study, monocentric, 134 patients with at least one abdominal imaging (for a total of 224 images).
Review of images by a radiologist blinded to clinical data, in case of disagreement with the initial analysis, consensus by an expert.
Consensus definition of imaging abnormalities.
Blinded clinical data collection of imaging data.
Univariate analysis.

Objectives

To study the results of abdominal imaging in COVID-19 patients.

Method

Retrospective cohort study, consecutive inclusion of COVID-19 patients admitted to a Boston hospital between March 27 and April 10. Collection of abdominal imaging results (from 7 days prior to admission to April 21) and clinical data from medical records.

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